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Symbol
Name
ID
Tnfrsf10b
tumor necrosis factor receptor superfamily, member 10b
MGI:1341090
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgG level
Decreased circulating antibody level
Paraproteinemia
Lymphadenopathy
Splenomegaly
Disease(s) Associated with TNFRSF10A
multiple myeloma

Mouse Phenotypes
enlarged thymus
increased NK cell number
increased circulating interferon-gamma level
increased circulating interleukin-12b level
abnormal interferon level
increased interleukin-12 secretion
increased tumor necrosis factor secretion
abnormal innate immunity
decreased susceptibility to Herpesvirales infection induced morbidity/mortality
decreased susceptibility to Herpesvirales infection
Availability Mouse Genotype
Tnfrsf10btm1Wnt/Tnfrsf10btm1Wnt
Tnfrsf10btm1Wsed/Tnfrsf10btm1Wsed

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory